While stopped at a roadside phone booth for transmitting his work through the Internet to the university, Professor Hideki Satomi finds a scrap of newspaper with the picture of his five-year-old daughter Nana in the obituary section.
Dr. Hattori and her husband watch footage of brain surgery experiments with Manchurian, Russian and Japanese guinea pigs that had been found in the basement of a wrecked hospital. Out of the blue, there is a white light and when they look back, they see they children Ota Miyuki and Kaori staring at the light. Years later, Miyuki vanishes from the Tama Medical University Hospital and her sister Kaori, Miyuki's boyfriend Motojima and detective Hirasawa are seeking her. However, Miyuki and the teenagers Kazochi, Takumi, Hattori and Rieko have been submitted to a nightmarish experiment by Dr. Hattori and her team with tragic results.
Sasha is a young woman from Beijing, studying in Nebraska. She flies to the Bay Area and meets up with friends, including Boshen, a gay man who was the lover of Yang, a member of Beijing's Opera who got Sasha pregnant four months before. She's made an appointment at a clinic for the next day. Boshen thinks he, she, Yang, and the baby can be a family. After a contentious dinner, Sasha meets X, a call girl on her way to a party with older men. Sasha goes too. Later, Sasha asks X to travel the world with her. Reality awaits the next day. As the annual St. Stupid's Day Parade passes by, Boshen accompanies Sasha to the clinic. What will she decide?
