Bruņojušies ar augsto tehnoloģiju spiegošanas un militāro aprīkojumu, G.I.JOE vienības īpašie aģenti ir uz pēdām ieroču tirgotājam Destro un noslēpumainai organizācijai "Kobra", kuru kopīgs mērķis ir pakļaut pasauli totālam haosam.
G.I. Joe komanda atgriežas! Viņiem jāstājas pretī Zartanam, viņa sabiedrotajiem un pasaules valstu līderiem, kurus tas pakļāvis.
When Utopia More discovers an ancient record that holds the key to unlocking the secrets of the universe, she becomes the target of the ruthless Gypsy Doc of the Pirate Guild. Utopia finds herself saved by the easy-going yet legendary space pirate, Cobra, whose custom made Psychogun makes him a force to be reckoned with. Together, the two of them attempt to stop Gypsy Doc (along with Cobra's revived arch-nemesis, Crystal Boy) and his efforts to steal the record and use its secrets to rule the universe.
