在未来世界，由于痛失爱子，天才科学家天马博士（尼古拉斯·凯奇 Nicolas Cage 配音）创造出了机械人阿童木（弗莱迪·海默 Freddie Highmore 配音），想以此来作为儿子的替身，寻找安慰。虽然，阿童木拥有博士儿子的情感和记忆，而且先进的程序还在不断完善其情绪，并让他富有同情心。可是，博士始终无法接受失子之痛，对阿童木也不能正确对待，并认为他不是人类而将其抛弃。阿童木沦落为无家可归的流浪儿，而且还备受军方的四处通缉，并最终被抓住。军方要求天马博士拿掉阿童木的能源，让它变成军方机器人的能源配备。在最后时刻，天马博士突然醒悟，并协助阿童木逃走。面对军方的围追堵截，阿童木奋起反抗，最终一场惊世大战一触即发。在不断的旅行过程中，阿童木也逐渐成长，他也接受了自己这机械与人类结合的设计，并肩负起全人类生死存亡的重任。
从小在左比星被当做王子养大的班达其实是地球人，他是在婴儿时期因为宇宙旅客船的事故落到了这个星球并被这里的王妃当做自己的孩子来抚养，然后知道自己身世秘密的班达开始了去往故乡地球的长途冒险。 这部动画是在为纪念日本电视居成立25周年而放送的“24小时电视节目：用爱拯救地球”中以特别动画（日本第一次放送的长达2小时的TV动画）的形式放送的。
主角是为了追捕暗杀了建设公团理事长的犯人而登上了太平洋海底列车马林·艾库斯布莱斯的私家侦探伴俊作。他与包括黑杰克在内的手冢治虫笔下的人气角色在一起，在列车上来了一次直达太古MU大陆的时间旅行！
A samurai lord has bartered away his newborn son's organs to forty-eight demons in exchange for dominance on the battlefield. Yet, the abandoned infant survives thanks to a medicine man who equips him with primitive prosthetics—lethal ones with which the wronged son will use to hunt down the multitude of demons to reclaim his body one piece at a time, before confronting his father. On his journeys the young hero encounters an orphan who claims to be the greatest thief in Japan.
In the year 2000, Dr. Boyton creates a super-robot in his deceased son's image. He calls the robot Astro Boy. Astro Boy can swim oceans, leap over mountains, even fly into space on his own power. However, Astro Boy can't replace his son. Dr. Boyton becomes dissatisfied with the boy robot and disowns him. Astro Boy is befriended by Dr. Packadermus J. Elefun of the Institute of Science, who guides him through his adventures. Endowed with super strength, rocket-powered flight, a selfless heart and a kind demeanor, Astro Boy fights a never-ending crusade against the forces of evil!
Astro is a robotic boy created by Dr. Tenma to replace his late son. When Tenma destroys his laboratory and shuts down Astro, the Ministry of Science revives him and tries to give him a normal life as a 6th-grade student who occasionally helps keep renegade robots from causing harm.
Japan in the near future suffers an unexplained major disaster. Five years later, reconstruction is well underway. Two young researchers at a university are pinning all their hopes on robot development. Now their new interpretation of the eternal hero Astro Boy up until his birth is just about to start!
A high-flying robot boy with superpowers gets ready to blast off into new adventures alongside Suzu and Astro Kitty to save the Earth from destruction.
A story set in the mid-1800's about a young doctor who has been trained in Western-style medicine and a young samurai who is trying to live up to the old traditions of his class and culture. The story is actually based upon real people - the doctor, Ryo-an, was Tezuka's great grandfather. The manga series was adapted to anime by Madhouse Studios and premiered in Japan on NTV on April 4, 2000.
